Prognathism



Autosomal-dominant inherited prognathism.

This individual, probably Charles VI or Carlos I, a Habsburg emperor inherited this malformation syndrome, from whom? – Neither his mother nor father showed evidence of this genetic mutation – his father’s father did! For a Medical Geneticist, the likelihood that this emperor represents a new gene mutation is remote! Guess what the alternatives are. A partial clue is suggested in Pandora Word Box companion site.