Index of Contents

LIST of CONTENTS

BELIEVE IT (OR NOT) – SPECIAL OBSERVATIONS
Illumination of de-novo and provocative notions.

Diagnosis Dilemma and Homage of Dr. Helen E. Nash (12 min.).
FISH (DNA specific diagnostic probes) – best use – why and how (21 min.).
Real Game of Thrones – Non-paternity – Habsburg Jaw and how they seized Spain (35 min.).
Sound of Music – Julie Andrews – Love – Dwarfs – A Medical Mystery (21 min.) continued in Medical Video Addendum (11 min.).
The Theme Ideonomy or Ideas implicit in Words (15 min.).

SIGNS
Transformation of signs into signals and dysmorphic syndromes – Gallery of ongoing postings of provocative images and perspectives.
Please search.

CLINICAL (4 SUBCATEGORIES)
Variants, dysmorphisms, malformations, deformations … embryopathies, fetopathies … dysplasias, neoplasias …

1 – VIDEO TRAILERS AND FREE FULL VERSIONS
Dysmorphology signs and Teratology – Genetics interpretations.

CEO – Why and How … in English – in Ukrainian.
About Basics of Dysmorphology (A) in English – in Ukrainian.
Introduction, essential notions and terminology – Part 1 of Genetics-Teratology-Dysmorphology (In Brief) tutorial (40 min.).
Signs, Signals, Pathogenesis, Etiology, Diagnosis – Part 2  of Genetics-Teratology-Dysmorphology (In Brief) tutorial (47 min.).
(Trailer part 1) – Dysmorphisms – Down syndrome infants – (in English – in Ukrainian).
(Trailer part 2) – Dysmorphisms – Down syndrome infants – (in English – in Ukrainian).
(Trailer part 3) – Dysmorphisms – Down syndrome post-infancy – (in English – in Ukrainian).

2 – Gallery of SIGNS
A collage of multiple images of a particular sign observed in a variety of persons (see alphabetic listing).

3 – Gallery of SYNDROMES – DIAGNOSES – VIDEOS

Galleries of multiple patients demonstrating combination of signs of particular syndromes/diagnoses.

13q- or Partial Deletion of the Long Arm of the Chromosome 13 – Gallery.
Achondroplasia – Syndrome Definition – Video (13 min.).
Albright Polyostotic Fibrous Dysplasia – Gallery.
Anophthalmia Bilateral – Short Presentation and Links.
Beckwith Wiedemann Macroglossia – Omphalocele Syndrome – Gallery.
Brachycephaly – Gallery.
Brachydactyly Type D Thumb – Gallery.
Chromosome 13 – Partial Deletion of the Long Arm (or 13q-) – Gallery.
Congenital Nephrotic Syndrome – Gallery.
Deletion Partial of the Long Arm of the Chromosome 13 or 13q- – Gallery.
Down Syndrome (DS) – Trisomy 21 (21+):
– Gallery – Signs (20 min.).
– DS – Signs – Virtual Clinic – Infants (Part 1 – 14 min.).
– DS Gallery – Hands – Feet.
– DS – Signs – Virtual Clinic – Infants (Part 2 – 13 min.).
– DS – Signs – Virtual Clinic – Child – Adult (Part 3 – 11 min.).
– DS – Video – Proficiency Test (42 min.).
Edward Syndrome Associated with Trisomy 18 (18+) – Gallery.
Encephalocele – Frontal – Gallery.
Fetal Alcohol Spectrum Disorders – Includes several virtual clinics videos.
Macroglossia – Omphalocele Beckwith Wiedemann Syndrome – Gallery.
Macroglossia – Perspectives – Gallery and Video (28 min.).
Male Turner Noonan – Gallery.
McCune-Albright Polyostotic Fibrous Dysplasia – Gallery.
Nephrotic Syndrome Congenital – Gallery.
Neurofibromatosis Type 1 (NF1) – Includes several virtual clinics videos (48 min.).
Partial Deletion of the Long Arm of the Chromosome 13 or 13q- – Gallery.
Plagiocephaly – see Brachycephaly.
Polyostotic Fibrous Dysplasia McCune-Albright – Gallery.
Sacral Teratoma – Gallery.
Syphilis – Gallery.
Teratoma Sacral – Gallery.
Warkany Trisomy Eight (8+) Mosaicism Spectrum – Gallery – Video (20 min.).

4 – Gallery of PATIENTS/FAMILIES
Galleries/videos illustrating patients/families with particular syndromes/diagnoses or unknown disorders.

7q- Syndrome – Gallery.
8+ Mosaicism – Warkany Syndrome – Gallery – Video (20:23).
13q- Multiple Malformations Complex – Gallery.
Achondroplasia Patient Development (12:57).
Acrocephalysyndactyly type 1 or Apert syndrome.
Albinism Oculo – Cutaneous Partial Chediak – Higashi – Gallery.
Anophthalmia Bilateral – Gallery.
Apert syndrome or Acrocephalysyndactyly type 1
Beckwith Wiedemann Macroglossia – Omphalocele Syndrome – Gallery:
– Patient 1.
– Patient 2.
Breech Footling Legs Syndrome – Gallery.
Brother – Sister Finger Tapering and Developmental Anomalies – Gallery.
Chediak – Higashi Albinism Oculo – Cutaneous Partial – Gallery.
Cleft Lower Lip – Gallery.
Deformations, Torticollis, etc. – Gallery.
Down Syndrome – Signs – Tele-Clinic – Infants (Part 1 – 14:11).
Down Syndrome – Signs – Tele-Clinic – Infants (Part 2 – 13:32).
Down Syndrome – Signs – Tele-Clinic – Child – Adult (Part 3 – 11:49).
Down Syndrome Hands – Feet – Gallery.
Down Syndrome High-Arched Palate – Gallery.
Dysmorphic Syndrome, FAS, etc. – Gallery.
Dysmorphic Syndrome – Tele-Clinic – Hirsutism – Synophrys – Flat Upper Lip (15:32).
Edward Syndrome Associated with Trisomy 18 (18+) – Gallery.
Footling Breech Legs Syndrome – Gallery.
Giant Congenital Melanocytic Nevus.
Higashi – Chediak Partial Oculo – Cutaneous Albinism – Gallery.
Holoprosencephaly (Patient A) – Gallery.
Holoprosencephaly (Patient B) – Gallery.
Hypospadias – Nipple Hypopigmentation – Gallery.
Lower Lip Cleft – Gallery.
Macroglossia – Omphalocele Beckwith Wiedemann Syndrome – Gallery.
Male Turner Noonan.
McCune-Albright Polyostotic Fibrous Dysplasia – Gallery.
McCune-Albright Polyostotic Fibrous Dysplasia – 2 – Gallery.
Median Solitary Median Maxillary Incisor (SMMI) Syndrome (14:22).
Multiple Endocrine Neoplasia (MEN) Syndrome Type 2A or Sipple – Gallery.
Neurofibromatosis-1 Complex – Acromegaly – Gallery.
Nipple Hypopigmentation – Hypospadias – Gallery.
Oculo – Cutaneous Partial Albinism Chediak – Higashi – Gallery.
Patau Syndrome (Patient A) – Gallery.
Patau Syndrome (Patient B) – Gallery.
Patau Syndrome (Patient C) – Gallery.
Polyostotic Fibrous Dysplasia McCune-Albright – Gallery.
Polyostotic Fibrous Dysplasia McCune-Albright – 2 – Gallery.
Purpura 1 -Gallery
Sacral Teratoma – Gallery
Sipple or Multiple Endocrine Neoplasia (MEN) Syndrome Type 2A – Gallery.
Teratoma Sacral – Gallery.
Torticollis, Deformations, etc. – Gallery.
Warkany Trisomy Eight (8+) Mosaicism Syndrome – Older Patient Gallery.
Warkany Trisomy Eight (8+) Mosaicism Syndrome – Younger Patient Gallery – Video (20:23).

SELECTED RESOURSES for STUDENTS and EDUCATORS
TUTORIALS, PRACTICUMS, CLINICAL VIDEOS, etc.

CLINICAL NOTES AND POINTS
Hippocrates of Kos, father of Modern Medicine, coined “Ars Longa Vita Brevis” – it is an art to define vital points in brief.

A “Positive” Examination of First Degree Relatives Can Over-Rule All Other “Negative” Investigations.
Age and chromosomal non-disjunction.
Cherish the Exceptional – Concurrence of Schwannomatosis and Brachydactyly Type D.
Concurrence of Schwannomatosis and Brachydactyly Type D – Cherish the Exceptional.
Deformation or disruption.
Dose (rate and amount) – sensitivity/repair (sex, age, ethnic) … e.g. alcohol, radiation.
Ear (Auricle) Signs as Signals of Renal Anomalies.
Epicanthus – ocular.
Face (facies) predicts the brain.
Face (facies) predicts the future.
Facies, nature of.
Family Variant, Dysmorphism, Malformation.
Function and Structure.
“Genetic”? “Counseling”? Dilemma.
Hypopigmented Nipples and Hypospadias – a Clue to Pathogenesis?
Hypospadias and Hypopigmented Nipples – a Clue to Pathogenesis?
Hypothesis – Neurofibromatosis Type 1 (NF1) and Temperature.
Mental Vision.
Muco-cutaneous Melanic Spots – High Cancer Risk – Hamartomatous Polyposis.
Neonatal Weight Loss.
Neurofibromatosis Type 1 (NF1) and Temperature – Facts and a Hypothesis.
Non-paternity in historic perspective – Med-Art.
Normal – Health.
Open minds and clinical examinations.
Palate – High Arched – Pseudo-Clefts – Torus (Tori).
Pharmacy – Pharmacology – Notions.
“Positive” Examination of First Degree Relatives Can Over-Rule All Other “Negative” Investigations.
Power and Punishments.
Principles of Teratology.
Short limbs – diagnosis – synthesis.
Short stature in historic perspective – Med-Art.
Sign > Signal > Syndrome > Pathogenesis … Etiology … Diagnosis.
Signs are objective and signals are subjective.
Signs illuminate the mind to create TRUE signals … syndromes … pathogenesis … etiology … diagnosis.
Tapered Fingers in a Brother-Sister Pair Provided a Clue to an X-linked Recessive Inherited Mutation.
Telorism – ocular – must be measured.
Temperature and Neurofibromatosis Type 1 (NF1) – Facts and a Hypothesis.
Teratology Principles.
Teratothanasia.
Treat or Wait? Purists vs. Humanists.
Trepanation – Avoiding by Palpation of Cranial Sutures.
Type and number of signals.
Upper Lip – Cupid’s Bow.
Vanishing twins – disruptions – median incisor.
Variants can be normal and normal can be variants.
Vision Mental.
Wait or Treat? Purists vs. Humanists.

LECTURES AND SPECIAL PRESENTATIONS
Notions resistant to erosions by time (in alphabetical order).

Birth defects congenital malformation prevention world day.
– Part 1 – 2017, March 3, Key points and press-release.
– Part 2 – Keynote presentation (28 min.): Prof. Wladimir Wertelecki and Dr. Lyubov Yevtushok – Strategies and Implementations (in Ukrainian).

Breastfeeding, Alcohol and Drug Use. Overview of lactation as a vehicle of teratogenic impacts of alcohol and drugs made by Dr. Claire Cole, a member of the international team implementing the CIFASD initiative in Ukraine sponsored by the National Institutes of Health concerned with alcohol teratogenesis. She coordinates investigations of alcohol impacts on mental development [ALCOHOL BABIES BREASTFEEDING FASD PUBLIC HEALTH]

A Child For Life. A 22-minute educational film explaining Fetal Alcohol Spectrum Disorder (FASD) and including interviews with experts, families and children affected by FASD. It was produced by NOFAS United Kingdom (NOFASUK) and translated into Ukrainian by Ukraine Works Ltd (Anne Linden, Director) [ALCOHOL BABIES CHILD CHILDREN DISORDERS FAMILIES FAMILY RELATIONS PUBLIC HEALTH INFANTS FASD].

Chornobyl – Polissia – Pregnancies – Children. A presentation made by Prof. Wladimir Wertelecki (OMNI-Net Ukraine) in 2016 in Lviv. It is dedicated to the 30th anniversary of the Chornobyl Nuclear Power Plant accident – in Ukrainian [IONIZING RADIATION, BECQUEREL, CS-137, CESIUM, NTD, MICROCEPHALY, EPIDEMIOLOGY].

Congenital malformations in Rivne Polissia and the Chornobyl accident. A presentation made by Prof. Wladimir Wertelecki at the Helen Caldicott Foundation Symposium “The Medical and Ecological Consequences of the Fukushima Nuclear Accident”, New York Academy of Sciences, 2013 – in English with French subtitles [IONIZING RADIATION, BECQUEREL, CS-137, CESIUM, NTD, MICROCEPHALY, EPIDEMIOLOGY].

Diagnosis of the Fetal Alcohol Syndrome. A presentation made by Prof. Kenneth L. Jones (Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA) at the Ukrainian Catholic University (Lviv, Ukraine) in April 2017 – In English with Ukrainian translation [FAS, FASD, DIAGNOSIS, PREVENTION].

Excerpts from “Genetic Counseling”. A report by Frank Clarke Fraser based on a Workshop on Genetic Counseling sponsored by the National Genetics Foundation, Inc., held in Washington, D.C., December 10-13, 1972 (Fraser FC. Genetic counseling. American Journal of Human Genetics. 1974;26(5):636-661) [GENETIC, COUNCELING].

Fetal Alcohol Spectrum Disorders (FASD) and Developmental Outcomes. A presentation made by Prof. Claire D. Coles (Emory University School of Medicine, Atlanta, GA, USA) at the Ukrainian Catholic University (Lviv, Ukraine) in April 2017 – In English with Ukrainian translation [FAS, FASD, DIAGNOSIS, PREVENTION, EDUCATION, PUBLIC HEALTH].

Fetal alcohol spectrum disorders – perspectives. A lecture delivered in 2013 by Dr. Kenneth Warren (Director of the National Institute of Alcohol and Alcohol Abuse) – in English with Ukrainian translation [FAS, FASD, PREVENTION, AMELIORATION, EDUCATION, PUBLIC HEALTH].

Folic acid flour fortification initiative. A story shown in a nation-wide transmission by Channel 24 (Ukraine, November 23, 2016) – in English and Ukrainian [PREVENTION, NTD, SPINA BIFIDA, PUBLIC HEALTH].

Intrauterine vascular disruption as a cause of birth defects. A presentation made in 2016 by Dr. Kenneth Jones (author of Smith’s Recognizable Patterns of Human Malformations, Department of Pediatrics, Division of Dysmorphology/Teratology, University of California, San Diego, School of Medicine, La Jolla, CA) – in English with Ukrainian translation [IUGR, TWIN, VANISHING, DEFORMATION, REVIEW, PLACENTA].

Josef Warkany – foundations of Teratology. A series of interviews with Josef Warkany (Austrian-American pediatrician known as the “Father of Teratology”) – in English [EXPERIMENTAL, TERATOGENESIS, NUTRITION, DIET, CRETINISM, IODINE, GOITER, ENVIRONMENT, ECOLOGY].

Neonatology – Teratology – Ukraine. A lecture of Prof. Wladimir Wertelecki (OMNI-Net Ukraine) for neonatologists and concerns the importance of early detection of developmental disabilities in children (2015, Chernivtsi, Ukraine) – in Ukrainian [NEWBORN, INFANT, MALFORMATIONS, DEFORMATIONS, SYNDROMES, DYSMORPHOLOGY, ANTICIPATORY, CARE, PREVENTION, FOLATE, FOLIC ACID, ALCOHOL].

Neural tube defects in Ukraine. In this video made in 2001, Profs. Yuriy Orlov, Ihor Baryliak, Dr. Halyna Skyban tell about the burden of neural tube defects in Ukraine – in Ukrainian [NTD, SPINA BIFIDA, PREVENTION, FORTIFICATION, FLOUR, FOLATE, FOLIC ACID].

MEDICAL WORDS – TERMINOLOGY AND IDEAS ILLUMINATED
Have fun with medical nomenclature (click below) – many words are like constellations of stars that illuminate clusters of ancient ideas that transcend time and linguistic barriers. Medical parlance relies upon empirical terminology and is best memorized by awareness of inherent ideonomy and etymology.

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