Dysmorphism > Ocular > Iris > Burshfiled spots

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Illustrated is a ring of depigmented iris spots (hypoplastic tissues) often seen in patients with Down Syndrome (DS)  (this sign as any other is not pathogonomic). Note that there is no epicanthic fold nor pronounced upward slant of the palpebral fissures.

See other illustrations of DS and Brushfield spots.

20151221 ww

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